My introduction to the world of Elder Scrolls was Oblivion, and it's still the only game in the series I've played for (far, far) more than ten minutes. (I know people loooves 'em some Morrowind, but it's clunky and difficult and frustrating as all hell on the Xbox...especially if you experienced Oblivion first.) It took me a while to get into it, and for a while I was tempted to put it down completely. I'd never partaken in a game so open-world and sandbox-y before, and it took some getting used to. To be honest, I never felt completely attached to my character or the main plot, but damned if I didn't thoroughly enjoy the world (despite the flat NPCs)..."world" being the key word. There's just so much out there to see and do in Cyrodiil- with hundreds of hours logged, there's still more to be discovered. Kind of amazing, really.
Skyrim is definitely on my must-get list (it hits 11/11/11). I'm hoping that those beautiful graphics of the trailer are matched to some compelling characters this go-round; if so, well. I just don't know what I'll do, but I'm sure I'll tell you all about it. WOW.